What Are Barrigel and Fiducial Markers?

Barrigel is a soft, absorbable gel injected between the prostate and rectum to create space, protecting the rectum from unnecessary radiation. Fiducial markers are tiny gold seeds placed in the prostate to act as reference points, ensuring that each radiation session precisely targets the tumor.

How They Work Together

Fiducial markers improve accuracy by guiding image-based targeting for radiation beams, while Barrigel acts as a shield, pushing the rectum safely away from high-dose areas. Together, they reduce side effects, protect bowel function, and improve treatment effectiveness.

Procedure Overview

  • Performed under local or light sedation in an outpatient setting
  • Markers placed via a transperineal or transrectal approach
  • Barrigel injected under ultrasound guidance
  • Entire process typically completed in under 45 minutes

Preparation

Preparation may include a light diet, stopping certain medications, and taking prescribed antibiotics. You will receive personalized instructions from your care team before your appointment.

Aftercare and Recovery

Most patients return to normal activities the same day. Mild tenderness or spotting may occur for a short period. There are typically no long-term limitations, and radiation therapy can begin soon after placement.

Benefits and Risks

Benefits include more precise radiation delivery, fewer bowel side effects, and improved treatment outcomes. Risks are minimal but can include temporary discomfort, minor bleeding, or infection at the insertion site.